Maternal Overnutrition Programs Central Inflammation and Addiction-Like Behavior in Offspring
نویسندگان
چکیده
منابع مشابه
Maternal immune activation transgenerationally modulates maternal care and offspring depression-like behavior
Gestational infection is increasingly being recognized for its involvement as causative mechanism in severe developmental brain abnormalities and its contribution to the pathogenesis of psychopathologies later in life. First observations in the widely accepted maternal immune activation (MIA) model based upon the systemic administration of the viral mimetic Polyinosinic:polycytidylic acid (poly...
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در طول دو قرن گذشته و ظهور روسیه بعنوان قدرتی بزرگ در عرصه جهانی و شروع رقابت با سایر قدرت های بین المللی و منطقهای خصوصا با ایران و عثمانی این ئکشور تلاش کرده است تاد از جمعیت کردها در این کشورها در راستای منافع خود بهره برداری کند در قرون 18 و 19 بارها بخشی از کردها برعلیه امپراطوری عثمانی توسط این کشور مورد استفاده قرار گرفت خصوصا در جنگ های سال 1790تا 1798. این ججنگ ها م.جب شد که بخشی از کر...
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Maternal obesity has long-term consequences for the development of hypothalamic neurones involved in energy homeostasis and the metabolic profile in offspring. In the present study, we compared the effects of maternal obesity induced by longstanding high-fat diet (HFD) with milder postnatal overfeeding during suckling induced by litter size reduction. Female Sprague-Dawley rats consumed chow (C...
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During pregnancy, women with polycystic ovary syndrome (PCOS) display high circulating androgen levels that may affect the fetus and increase the risk of mood disorders in offspring. This study investigated whether maternal androgen excess causes anxiety-like behavior in offspring mimicking anxiety disorders in PCOS. The PCOS phenotype was induced in rats following prenatal androgen (PNA) expos...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2018
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2018/8061389